Head of the Institute

Prof. Dr. Matthias Schwab

Major Projects

  • Pharmacogenomics / Epigenetics of drug metabolizing enzymes, drug transporters and nuclear receptors  
  • Pharmacogenomics of anticancer and immunosuppressive drugs
  • Drug Interaction
  • Pediatric clinical pharmacology
  • Novel methodologies in genomic research and molecular diagnostics

Book Editor

Kiess W., Schwab M., van den Anker J. (eds) Pediatric Pharmacotherapy. Handbook of Experimental Pharmacology, vol 261. Springer, Cham, 2020
Schwab M, Kaschka WP, Spina E (eds.). Pharmacogenomics in Psychiatry. Advances in Biological Psychiatry. Vol. 25. Karger, 2010
Seyberth WH, Rane A, Schwab M (eds.) Pediatric Clinical Pharmacology, Handbook of Experimental Pharmacology. 14th Edition, Springer, 2011


Curriculum Vitae

Education and Professional Career


Coopted Professor at the faculty of mathematics and natural sciences - department of pharmacy and biochemistry, University of Tuebingen


Offer as Full Professor and Chair for Clinical Pharmacology, Karolinska University, Sweden in combination with a clinical position as Senior Physician at Karolinska University Hospital

2007 - present

Professor and Chair of Clinical Pharmacology, Eberhard Karl University Tuebingen, Germany

Head of the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and the Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tuebingen


Offer as Full Professor and Chair for Clinical Pharmacology, Medical University Innsbruck, Austria

2005 - 2006

Visiting Professor, St. Jude Children’s Research Hospital, Department of Pharmaceutical Sciences, Memphis, Tennessee, USA (Prof. W.E. Evans)


Habilitation for „Clinical Pharmacology and Paediatric Pharmacology“ at the Eberhard-Karls University Tuebingen

2001 - 2005

Senior physician and Head of the Research Unit for Clinical Trials and Drug Information Centre at the Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (Prof. Dr. M. Eichelbaum)

2000 - 2005

Coordinator of the research focus "Pharmacogenetics" at the Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (Prof. Dr. M. Eichelbaum)


Board Certification: Clinical Pharmacology


Board Certification: Paediatrics and Adolescent Medicine

Special qualification as emergency physician for newborns (acc to DÖGNPI), education for paediatric nephrology, additional certification in: Paediatric ultrasonography of the thyroid gland of head and neck, of the gastrointestinal tract and of female genitals, certification in addiction medicine in children and adolescents, certification in radiological diagnostics for thoracic organs, certification in basic psychosomatic medicine

1995 - 2001

Fellow in clinical pharmacology at the Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany (Prof. Dr. M. Eichelbaum)

1993 - 1995

Senior house officer at the University Hospital of Children and Adolescents, Friedrich-Alexander University of Erlangen-Nuernberg, Erlangen, Germany (Prof. Dr. C. Stehr)


State Licence as medical doctor


Doctor`s degree of medicine, Institute of Toxicology and Pharmacology, University Erlangen Nuernberg (Prof. Dr. R. Böcker / Prof. Dr. C. Estler).

1990 - 1993

Civilian service as house officer and later as senior house officer at the Children's Hospital, Nuernberg, Germany (Prof. Dr. H. Gröbe)

1983 - 1990

Study of medicine, Friedrich-Alexander University of Erlangen-Nuernberg

Appointments and Elected Offices

  • Academy of Science and Literature Mainz, Germany Commission for Medical Research (2014-present, chair since 2015)
  • Baden-Wuerttemberg-International, Germany Elected Committee for the joint partnership between BW and Kanagawa (Japan) “Technologies in an aging society”, Yokohama (2015)
  • British Phaarmacological Society, Fellow 2021
  • European Assocation of Clinical Pharmacology and Therapy (EACPT) Council of EACPT (2010-present, re-election 2015) Executive Committee (2010-present, re-election 2015)
  • European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) EFLM-ESPT working group on Personalized Laboratory Medicine (WG-PLM) (2012-present)
  • European Health Foundation (EHF) Board of Trustees (2013-present)
  • European Medicines Agency (EMEA) CPMP Pediatric Expert Group (PEG): Extraordinary member (2001-2004)
  • German Federal Institute of Drugs and Medicinal Products (BfArM) Expert Group "Drugs for Children and Adolescents" according to AMG (2004-present, re-calls in 2006, 2009, 2011 and 2013): Full Member and Vice Chair
  • German Federal Institute of Drugs and Medicinal Products (BfArM) Member of the Scientific Advisory Board (2022 - 2025)
  • German Medical Association (AkdÄ) Drug Commission (2007-present)
  • German Morbus Crohn/Colitis Ulcerosa Association DCCV e.V. Scientific Advisory Board (2014-present)
  • German Society of Child and Adolescent Medicine Committee of Drug Safety (1998-present)
  • German Society of Clinical Pharmacology (DGKliPha) Chair (2013-2018, re-election 2015)
  • German Society of Experimental and Clinical Pharmacology and Toxicology (DGPT) President (2015)
  • Institute of Digital Medicine (IDM Foundation) Stuttgart Executive Board (2011-2013) Board of trustees (2013-present)
  • Interfaculty Centre of Pharmacogenomics and Drug Research (ICEPHA), Tübingen-Stuttgart Scientific Board and Vice Chair (2006-present)
  • International Union of Basic and Clinical Pharmacology (IUPHAR) Div. Clinical Pharmacology/Sub-Committee Pharmacogenetics (2008-present) Drug Metabolism and Transporter Section Executive Board (2010-2014 Councillor, 2014-2018 Vice Chair, since 2018 Chair)
  • Medical Chamber of the State Baden-Württemberg Ethical committee (2004-present) Widerspruchsausschuss postgraduate training (2015-2019)
  • Natural and Medical Sciences Institute (NMI), non-profit public-law foundation, Reutlingen, Germany Deputy Chairman (2010-present)
  • Robert Bosch Stiftung, Stuttgart, Germany, Selection Committee "Fast Track - Exzellenz und Führungskompetenz für Wissenschaftlerinnen auf der Überholspur" (2011,2015,2017)
  • University of Helsinki, International Evaluation Board of the Election of the Erkko Professorship (2014
  • Verbund Klinische Pharmakologie in Deutschland e.V., Chair of the 17th and 18th Annual Meeting 2016 and 2017
  • Vienna Science and Technology Fund, Vienna, Austria, International Evaluation Board of Life Sciences Call 2016 Personalized Medicine (2015-2016)

Institutional Committees

Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart and Robert-Bosch-Hospital, Stuttgart, Germany

  • Board of Scientists (1999-2005), Chair (2007- present)
  • Medical Executive Board (2007-present)

Eberhard Karls University Tuebingen, Germany

  • Committee for Research Strategy & Coordination, Rektorat University Tübingen (2012-present)
  • Board of Members of the Comprehensive Cancer Center (CCC) University Hospital Tübingen (2009-present)
  • Council of the Medical Faculty University Tübingen (2010-present)
  • Extended Research Committee Med. Faculty University Tübingen (2008-present)

Community Service

  • Committee for qualification as medical specialist in clinical pharmacology, Regional Medical Chamber Nordwürttemberg (2013-present)

Public (regional, federal) appointments
Federal German Ministry of Health, Berlin

  • Gendiagnostikkommission (2010-2013)
  • Committee of Experts on Drug Prescription (2013-2017)

Other appointments and Advisory boards

  • Scientific Advisory Board, Reference Institute for Bioanalytics (Foundation for Pathobiochemistry and Molecular Diagnostics), Bonn (2014-present)
  • Expert Group "HEXAL-Iinitiative drugs for children" (2004-2010)
  • Initiative Medicines for Children e.V. (IKAM) (2012-present)

Awards and Honors

  • Adjunct Professor for "Clinical Pharmacology" and "Biochemistry" at Yerevan State Medical University, Armenia (2018-2024)
  • Thomson Reuters/Clarivate Highly Cited Researchers, rubric “Pharmacology and Toxicology”/"Cross Field" (2015/2016/2018/2020)
  • Robert-Pfleger Research Award (2016)
  • Conferment of the “Staufer-Medal” by the Prime Minister of Baden Württemberg (2015)
  • Celebratory Speech ("Vom Wert der Arznei - Wege zu einer zielgerichteten Therapie") at the Annual Meeting of the Academy of Science and Literature, Mainz, Germany (2014)
  • Member of the German National Academy of Sciences ‘Leopoldina’ (2014)
  • Most cited German pharmacologist in Europe (LabTimes, 2013)
  • Member of Faculty of 1000 Prime, Section Pharmacogenomics (2012-2016)
  • Full Member of the Academy of Science and Literature, Mainz, Germany (2012)
  • Authorization of IKP (M. Schwab) as a training center for ‘Drug information’ by the Chamber of Pharmacists of the State Baden-Württemberg (2010)
  • EACPT Key lecture “Personalized Medicine beyond Pharmacogenetics”, 16th World Congress on Basic and Clinical Pharmacology, Copenhagen, Denmark (2010)
  • Most cited pharmacologist in German-speaking countries (Laborjournal, 2009)
  • Galenus von Pergamon Award (2005)
  • Friedrich Hartmut Dost Award (2004)
  • Scholarship according to the "Bayerischen Begabtenförderungsgesetz" (1983-1990)

Scientific Journal Editorial Board Memberships

Editor in Chief

  • Pharmacogenetics & Genomics
  • Drug Research

Section Editor

  • "Pharmacogenomics and Personalized Medicine" of Genome Medicine
  • Monatsschrift Kinderheilkunde, Section Editor „Drug Therapy” (2015-2019)

Editorial Boards

  • British Journal of Clinical Pharmacology, Member of the International Editorial Board (2013-present)
  • Clinical Chemistry (2008-2014)
  • Therapeutic Drug Monitoring
  • Journal of Personalized Medicine
  • Biomedicine Hub (2017-2019)
  • Clinical Pharmacology & Therapeutics

Book Editor

  • Kiess W., Schwab M., van den Anker J. (eds) Pediatric Pharmacotherapy. Handbook of Experimental Pharmacology, vol 261. Springer, Cham, 2020
  • Schwab M, Kaschka WP, Spina E (eds.). Pharmacogenomics in Psychiatry. Advances in Biological Psychiatry. Vol. 25. Karger, 2010
  • Seyberth WH, Rane A, Schwab M (eds.). Handbook of Experimental Pharmacology. Pediatric Clinical Pharmacology, 14th Edition, Springer, 2011

Member of National and International Research Consortia

  • DFG KFO 274 Thrombozyten - Molekulare Mechanismen und translationale Bedeutung, University of Tuebingen, Germany
  • DFG German-African Cooperation Projects in Infectious diseases, University Hospital Tuebingen, Germany
  • GANI_MED (Greifswald Approach to Individualized Medicine), German Federal Ministry for Education and Research (BMBF)
  • German Center for Infection and Research (Dt. Zentrum für Infektionsforschung, IZF)
  • German Consortium for Translational Cancer Research (Dt. Konsortium für Translationale Krebsforschung, DKTK)
  • International Clinical Pharmacogenetics Implementation Consortium (Member, USA)
  • International Clopidogrel Consortium (Member of Steering Committee, Baltimore, USA)
  • International PGx nomenclature working group (USA- Centers for Disease Control and Prevention)
  • International TPMT nomenclature committee (
  • Kinacept consortium: Novel anti-inflammatory compounds for autoimmune diseases (FP7-SME-1)
  • NeuRoSIS-Consortium: Efficacy and Safety of Inhaled Budesonide in very Preterm Infants at risk for Bronchiopulmonary Dysplasia (FP5 Health 2009)
  • PREDICT: Holistic Multi-Scale Modeling of Targeted Protein Therapeutics Action: Towards Predicting Effective Treatment of Cancer (BMBF)
  • SFB 685 “Immunotherapy: Molecular Basis and Clinical Application”, University of Tuebingen, Germany
  • U-PGx consortium: Making actionable pharmacogenomics data and effective treatment optimization accessible to every European citizen“(EU, Horizon 2020)
  • Verbundprojekt FORSYS-Kooperation „Ein systembiologischer Ansatz zur prädiktiven Krebstherapie“ (BMBF)
  • Verbundprojekt INFORM „Individualized Therapy for Relapsed Malignancies in Childhood“, Deutsche Krebshilfe e.V. (Deutsche Kinderkrebsstiftung, DKTK)
  • Virtual Liver Network (BMBF)

Coordinator of Training Site and Research Networks

  • EU FP7-People-ITN: Marie Curie Initial Training Network “Fighting Drug´Failure”. Lead Applicant and Consortium heads: Schwab M & Brauch H
  • U-PGx consortium: Making actionable pharmacogenomics data and effective treatment optimization accessible to every European citizen“(EU, Horizon 2020, M. Schwab, Vice Chair)
  • BMBF (01ZP0502): Open label, prospective, observational, multi-centre trial in postmenopausal, hormonereceptor positive breast cancer patients treated with either tamoxifen or an aromatase inhibitor (IKP211). Study PI (since 2007)
  • ICEPHA Minigraduate College Membrane associated drug targets in Oncology
  • BMBF Verbundprojekt “Genotype and phenotype guided supplementation of TAMoxifen standard therapy with ENDOXifen in breast cancer patients (TAMENDOX)

Membership of Professional Bodies

  • International Society of the Study of Xenobiotics (ISSX)
  • American Society for Clinical Pharmacology and Therapeutics (ASCPT)
  • European Society for Developmental, Perinatal & Pediatric • Pharmacology (ESDP)
  • German Society of Clinical and Experimental Pharmacology (DGPT)
  • German Society of Child and Adolescent Medicine (DGKJ)
  • German Society of Nephrology (GPN)

Reviewing Activities with Journals

  • Aliment Pharmacol Ther
  • Am J Human Genet
  • Ann Intern Med
  • Anticancer Drugs
  • Basic & Clin Pharmacol & Toxicol
  • Biol Neonate
  • Biochem Pharmacol
  • Blood
  • Breast Cancer Res Ther
  • Br J Clin Pharmacol
  • Br J Pharmacol
  • Br Med J
  • Cancer Res
  • Clin Chemistry
  • Clin Cancer Res
  • Clin Pharmacol Therapeut
  • Clin Pharmacokinet
  • Diabetes
  • Diabetologica
  • Drug Metab Dis
  • Eur J Clin Pharmacol
  • Eur J Human Genet
  • Expert Opin Drug Safety
  • Gastroenterology
  • Genes and Immunity
  • Gut
  • Human Mutat
  • Human Mol Genet
  • Inflam Bowel Dis
  • Int J Cancer
  • Intervent Cardiol
  • JAMA
  • J Am Soc Nephrol
  • J Clin Oncol
  • J Clin Pharmacol
  • J Hepatol
  • J Natl Cancer Institute
  • J Pharmacol Exp Ther
  • Lancet Oncol
  • Leukemia
  • Mol Pharmacol
  • Nature
  • Nature Genet
  • N Engl J Med
  • Oncogene
  • Pediatrics
  • Pediatr Nephrol
  • Pharmacogenetics and Genomics Pharmacogenomics
  • Pharmacogenomic J
  • Placenta
  • PNAS
  • The Lancet
  • Therapeut Drug Monitor
  • Xenobiotica