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Simeon Rüdesheim
Scientist

Simeon Rüdesheim, Pharmacist


Tel +49-681-302 2284

Major Projects

  • Physiologically based pharmacokinetic (PBPK) modeling of drug-drug, drug-gene and drug-drug-gene interactions

Selected References

Rüdesheim S, Selzer D, Fuhr, U., Schwab M., Lehr T. Physiologically based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups. CPT Pharmacometrics Syst Pharmacol 2022; (accepted manuscript)

Türk Denise, Fuhr Laura Maria, Marok Fatima Zahra, Rüdesheim Simeon, Kühn Anna, Selzer Dominik, Schwab Matthias, Lehr Thorsten. Novel models for the prediction of drug-gene interactions. Expert Opin Drug Metab Toxicol. 2021;17(11):1293-1310. doi: 10.1080/17425255.2021.1998455. PMID: 34727800.
Rüdesheim S, Wojtyniak JG, Selzer D, Hanke N, Mahfoud F, Schwab M, Lehr T. Physiologically based pharmacokinetic modeling of metoprolol enantiomers and α-hydroxymetoprolol to describe CYP2D6 drug-gene interactions. Pharmaceutics 2020;12(12):1200

Curriculum Vitae

Education and Professional Career

Since 2022

Scientific Researcher, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart and University of Tübingen

Since 2019

PhD student, Clinical Pharmacy, Saarland University, Saarbrücken, Germany and Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart and University of Tübingen

2018-2020

M.Sc. Pharmacy, Clinical pharmacy working group, Saarland University, Saarbrücken, Germany
Thesis: “Physiologically based pharmacokinetic modeling of the CYP2D6 substrate metoprolol”

2014-2018

Studies in Pharmacy, Saarland University, Saarbrücken, Germany