About

The Deptartment of Internal Medicine and Nephrology at the Robert Bosch Hospital (RBK) is a leading German centre for complex nephrology with growing international visibility. Research strategy integrates three pillars: clinical trials, a granular real-world data and AI platform, and translational research in collaboration with IKP. Since Introducation of a fully digital patient record at RBK (2017), we have built one of Germany’s most detailed inpatient kidney datasets. The platform captures longitudinal clinical data, procedures, medications, structured information from clinical documents, etc. Our concept enables the integration of clinical trials, high-resolution clinical data and mechanistic laboratory research to strengthen RBK as an international centre for translational nephrology research.

Heads

Prof. Dr. Jörg Latus
Chief Physician General Internal Medicine and Nephrology; Research Group Leader Advancing Precision Nephrology
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PD Dr. Moritz Schanz
Research Group Leader Advancing Precision Nephrology
Tel+49-711-8101 2157
moritz.schanz@rbk.de

Team Members

Prof. Markus Ketteler
Senior Scientist
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Nico Schmid
Scientist
nico.schmid@rbk.de
Dr. Tina Oberacker
Scientist
Tel+49-711-8101 2833
tina.oberacker@rbk.de
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Dr. Leonie Kraft
Scientist
leonie.kraft@rbk.de
Dr. Severin Schricker
Scientist
severin.schricker@rbk.de
Dagmar Biegger
Technical Assistant
Tel+49-711-8101 2188
dagmar.biegger@ikp-stuttgart.de
Andrea Schwab
Study Coordinator
Tel+49-711-8101 5874
andrea.schwab@rbk.de
Kathrin Kauselmann
Study Nurse
Tel+49-711-8101 4235
kathrin.kauselmann@rbk.de

Selected publications of the Research Group

  • Kraft L, Oberacker T, Schwab A, Brunner L, Stäbler C, Kitterer D, Braun N, Tremmel R, Schricker S, Latus J, Schanz M. Clinical course up to 20 years after hantavirus infection. Nephrol Dial Transplant. 5(41):859–865, 2026. doi: 10.1093/ndt/gfaf212.
  • Kraft L, Oppold J, Kitterer D, Braun N, Kimmel M, Twardowski L, Biegger D, Oberacker T, Schwab A, Merz S, Wirkus K, Schulte K, Schmitt R, Kielstein JT, Eden G, Schmid N, Schricker S, Latus J, Schanz M. Changing microbiology and outcomes of PD-associated peritonitis over four decades. Clin Kidney J. 1(19):sfaf387, 2026. doi: 10.1093/ckj/sfaf387.
  • Wülfrath HS, Voran JC, Kolbrink B, Kakavand N, Samson-Himmelstjerna FA, Esser G, Thomsen S-Y, Schrumpf T, Kielstein JT, Eden G, Latus J, Schanz M, Mitzner S, Frank D, Schmitt R, Schulte For The TriPoD Study Group K. Peritoneal dialysis catheter implantation in Germany - retrospective, nationwide analysis of all cases (2011-2021). Perit Dial Int):8968608261418175, 2026. doi: 10.1177/08968608261418175.
  • Christ M, Schmid N, Alscher MD, Heidrich C, Rylski B, Latus J, Goebel N, Schanz M. Attention to early stages: predicting acute kidney injury in a post cardiosurgical ICU setting using an inclusive time-to-event model. Comput Biol Med. Pt B(192):110336, 2025. doi: 10.1016/j.compbiomed.2025.110336.
  • Latus J, Mayer G, Narvaez C, Manu M, Jesus S, Ruessmann D, Manenti L. Real-world safety of difelikefalin for chronic kidney disease-associated pruritus: initial insights from a European managed access programme. Clin Kidney J. 10(18):sfaf297, 2025. doi: 10.1093/ckj/sfaf297.
  • Perkovic V, Barratt J, Rovin B, Kashihara N, Maes B, Zhang H, Trimarchi H, Kollins D, Papachristofi O, Jacinto-Sanders S, Merkel T, Guerard N, Renfurm R, Hach T, Rizk DV. Alternative Complement Pathway Inhibition with Iptacopan in IgA Nephropathy. N Engl J Med. 6(392):531–543, 2025. doi: 10.1056/NEJMoa2410316.
  • Schanz M, Seikrit C, Hohenstein B, Zimmermann A, Kraft L, Schricker S, Berger S, Schwab A, Oberacker T, Latus J. First real-world evidence of sparsentan efficacy in patients with IgA nephropathy treated with SGLT2 inhibitors. Clin Kidney J. 1(18):sfae394, 2025. doi: 10.1093/ckj/sfae394.
  • Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, Emberson JR, Preiss D, Judge P, Mayne KJ, Ng SYA, Sammons E, Zhu D, Hill M, Stevens W, Wallendszus K, Brenner S, Cheung AK, Liu Z-H, Li J, Hooi LS, Liu W, Kadowaki T, Nangaku M, Levin A, Cherney D, Maggioni AP, Pontremoli R, Deo R, Goto S, Rossello X, Tuttle KR, Steubl D, Petrini M, Massey D, Eilbracht J, Brueckmann M, Landray MJ, Baigent C, Haynes R. Empagliflozin in Patients with Chronic Kidney Disease. N Engl J Med. 2(388):117–127, 2023. doi: 10.1056/NEJMoa2204233.
  • Kraft L, Schanz M, Schricker S, Ketteler M, Mayer G, Rostoker G, Manenti L, Schwenger V, Latus J. The first real-world experience of IV difelikefalin to treat chronic kidney disease-associated pruritus in haemodialysis patients. : JEADV, 2023. doi: 10.1111/jdv.19105.
  • Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae D-W, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, Trachtman H. Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis. N Engl J Med. 26(389):2436–2445, 2023. doi: 10.1056/NEJMoa2308550.
  • Schmid N, Ghinescu M, Schanz M, Christ M, Schricker S, Ketteler M, Alscher MD, Franke U, Goebel N. Algorithm-based detection of acute kidney injury according to full KDIGO criteria including urine output following cardiac surgery: a descriptive analysis. BioData Min. 1(16):12, 2023. doi: 10.1186/s13040-023-00323-3.